Description

(S)-2-Fluoro-1,2,2-Triphenylethylamine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its unique stereochemistry and fluorine substitution, which are critical for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Utilized in the development of advanced, fluorinated agrochemicals where the stereocenter can influence herbicidal or insecticidal activity and environmental fate.
• Material Science: Investigated as a monomer or functional additive for creating specialty polymers with tailored optical or electronic properties.
• Academic & Process Chemistry: Employed in university and industrial labs for methodological studies in fluorination chemistry and stereoselective synthesis.

Basic Information

Product Name	(S)-2-Fluoro-1,2,2-Triphenylethylamine
CAS No.	75198-01-5
Molecular Formula	C20H18FN
Molecular Weight	291.36 g/mol
Synonyms	(S)-α-Fluoro-α-phenylbenzenemethanamine; (S)-1,1,2-Triphenyl-2-fluoroethanamine; (S)-2-Fluoro-1,1,2-triphenylethanamine; (S)-FTPEA; (S)-FTPA; Benzenemethanamine, α-fluoro-α-phenyl-, (αS)-; (S)-(-)-2-Fluoro-1,2,2-triphenylethylamine
EINECS	Contact for details

Quality Control

Our (S)-2-Fluoro-1,2,2-Triphenylethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess (ee), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.