Description

Acetonyl-Coenzyme A is a specialized biochemical reagent and a key intermediate in metabolic pathways, particularly in ketone body metabolism and fatty acid biosynthesis. This high-purity compound is essential for researchers and manufacturers requiring precise enzymatic cofactors for biochemical assays and synthesis. It is primarily utilized in pharmaceutical R&D, academic research, and the production of fine chemicals where enzymatic processes are critical.

Application

• Biochemical Research: Used as a critical substrate or cofactor in enzymatic studies of acetoacetate metabolism and ketogenesis.
• Pharmaceutical Development: Serves as an intermediate in the synthesis of novel drug candidates targeting metabolic disorders.
• Diagnostic Reagent Manufacturing: Incorporated into enzymatic assay kits for clinical diagnostics related to metabolic function.
• Enzyme Mechanism Studies: Employed to investigate the activity and kinetics of acyl-CoA synthetases and transferases.
• Metabolic Pathway Analysis: Essential for in vitro reconstruction and analysis of fatty acid oxidation and ketone body utilization pathways.
• Fine Chemical Synthesis: Acts as a building block for the synthesis of complex, chirally pure molecules in biotechnology.

Basic Information

Product Name	Acetonyl-Coenzyme A
CAS No.	75179-85-0
Molecular Formula	C₂₄H₄₀N₇O₁₇P₃S
Molecular Weight	847.59 g/mol
Synonyms	Acetonyl-CoA; 3-Oxobutyl-CoA; 1-(3-Oxobutyl)-Coenzyme A; S-Acetonylcoenzyme A; CoA S-acetonide; Acetoacetyl-CoA analog; 3-Ketobutyl-coenzyme A
EINECS	Contact for details

Quality Control

Our Acetonyl-Coenzyme A is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Assayed (Enzymatic)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.