Description

Tauroselcholic Acid CAS NO 75018-71-2 is a conjugated bile acid derivative formed from the combination of selcholic acid and taurine. This compound is of significant interest in pharmaceutical research and development, particularly for its role in studying bile acid metabolism and transport. It serves as a critical intermediate and reference standard for the synthesis and analysis of novel therapeutic agents targeting liver and gastrointestinal functions. Key industries that utilize this high-purity biochemical include pharmaceutical R&D, academic research institutions, and manufacturers of diagnostic reagents.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel therapeutic agents targeting bile acid receptors (e.g., FXR, TGR5).
• Biochemical Research: Serves as a critical reference standard in studies of bile acid metabolism, transport, and signaling pathways.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and reagents for clinical assays measuring liver function and bile acid profiles.
• Cell Culture & In Vitro Studies: Utilized in hepatocyte and enterocyte culture models to investigate cholestasis, drug-induced liver injury, and intestinal absorption.
• Metabolomics & Analytical Chemistry: Acts as a high-purity standard for Liquid Chromatography-Mass Spectrometry (LC-MS) and other analytical techniques in metabolomic profiling.

Basic Information

Item	Details
Product Name	Tauroselcholic Acid
CAS No.	75018-71-2
Molecular Formula	C₂₆H₄₅NO₇S
Molecular Weight	515.71 g/mol
Synonyms	Tauroselcholate; Tauroselcholic acid sodium salt (derivative); 3α,7α,12α-Trihydroxy-5β-cholan-24-oyltaurine; N-[(3α,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]taurine; TSCA; Selcholic acid taurine conjugate
EINECS	Contact for details

Quality Control

Our Tauroselcholic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis, to ensure it meets the stringent requirements for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.