Description

1-Palmitoyl-2-(7-(4-Azido-2-Nitrophenoxy)Heptanoyl)-Sn-Glycero-3-Phosphocholine is a specialized, photoactivatable phospholipid derivative designed for advanced biochemical and biophysical research. This compound is engineered to enable the covalent cross-linking of lipid membranes upon exposure to light, a critical function for studying membrane dynamics and protein-lipid interactions. It is an essential reagent for researchers in structural biology, membrane biophysics, and the development of targeted drug delivery systems, where precise control over membrane architecture is required.

Application

• Membrane Protein Research: Used as a photo-crosslinker to trap and stabilize transient interactions between membrane proteins and their lipid environment for structural analysis.
• Liposome & Lipid Nanoparticle Engineering: Incorporated into lipid bilayers to create light-triggered, stabilized vesicles for controlled release studies and advanced drug delivery platform development.
• Model Membrane Studies: Employed in the construction of artificial membranes (e.g., supported lipid bilayers, black lipid membranes) to investigate fundamental properties like fluidity, fusion, and phase separation.
• Cell Surface Labeling: Facilitates the covalent tagging of cell surface components upon photoactivation, allowing for the tracking and isolation of membrane-associated molecules.
• Bioconjugation & Probe Development: Serves as a key intermediate for synthesizing fluorescent or affinity-tagged phospholipid probes for imaging and pull-down assays.
• Material Science: Applied in the surface functionalization of biomaterials to create bioactive coatings that mimic natural cell membranes.

Basic Information

Product Name	1-Palmitoyl-2-(7-(4-Azido-2-Nitrophenoxy)Heptanoyl)-Sn-Glycero-3-Phosphocholine
CAS No.	74970-86-8
Molecular Formula	C₄₁H₇₂N₅O₁₂P
Molecular Weight	858.01 g/mol
Synonyms	ANP-PC; 1-Palmitoyl-2-(7-(4-Azido-2-Nitrophenoxy)heptanoyl)-sn-glycero-3-phosphocholine; Photoactivatable PC; 4-Azido-2-nitrophenyl-phosphatidylcholine; NAP-PC; ANP-DPPC; Azido Nitrophenyl Phosphatidylcholine; Light-activatable Phosphatidylcholine
EINECS	Contact for details

Quality Control

Every batch of 1-Palmitoyl-2-(7-(4-Azido-2-Nitrophenoxy)Heptanoyl)-Sn-Glycero-3-Phosphocholine is produced and analyzed under strict quality protocols to ensure the high purity and consistency required for sensitive research applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and functional activity verification. Certificates of Analysis (COA) detailing lot-specific results are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.