Description

(2S,3S)-(-)-2,3-Butanediol Di-p-Tosylate is a high-purity chiral building block and protecting group reagent of significant synthetic utility. This compound is valued for its role in the stereoselective synthesis of complex molecules, particularly in pharmaceutical and fine chemical research. It is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require enantiomerically pure intermediates for developing active ingredients and specialty chemicals.

Application

• Chiral Auxiliary and Building Block in the asymmetric synthesis of pharmaceuticals and natural products.
• Key Intermediate for the preparation of enantiomerically pure ligands, catalysts, and macrocyclic compounds.
• Protecting Group Reagent for diols in multi-step organic synthesis, offering selective deprotection pathways.
• Research & Development of novel active pharmaceutical ingredients (APIs) with defined stereochemistry.
• Synthesis of Specialty Polymers and advanced materials requiring chiral monomers.
• Production of Fine Chemicals and agrochemical intermediates where stereochemical integrity is critical.

Basic Information

Product Name	(2S,3S)-(-)-2,3-Butanediol Di-p-Tosylate
CAS No.	74839-83-1
Molecular Formula	C20H26O6S2
Molecular Weight	426.55 g/mol
Synonyms	(2S,3S)-2,3-Dihydroxybutane-1,4-diyl bis(4-methylbenzenesulfonate); (-)-2,3-Butanediol Di-p-Tosylate; (2S,3S)-(-)-2,3-Butanediol Ditosylate; (2S,3S)-Butane-1,2,3,4-tetrayl tetrakis(4-methylbenzenesulfonate) (incorrect but common misnomer); L-(+)-2,3-Butanediol Di-p-Tosylate (enantiomer); Ditosyl-(2S,3S)-2,3-butanediol; (2S,3S)-2,3-Bis[(4-methylphenyl)sulfonyloxy]butane
EINECS	Contact for details

Quality Control

Our (2S,3S)-(-)-2,3-Butanediol Di-p-Tosylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for synthetic chemistry. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are provided to guarantee reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.