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1-Stearoyl-3-Myristoyl-Glycero-2-Phosphocholine CAS NO 74838-88-3


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CAS No.:74838-88-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Stearoyl-3-Myristoyl-Glycero-2-Phosphocholine is a high-purity, synthetic phospholipid with a defined acyl chain composition, offering superior consistency for advanced research and formulation. This compound is critical for creating model membrane systems with specific biophysical properties, enabling precise studies of lipid-protein interactions and membrane dynamics. It is an essential material for pharmaceutical researchers, formulation scientists, and diagnostic developers working on liposomal drug delivery, membrane biophysics, and advanced biomimetic materials.

Application

  • Liposomal Drug Delivery Systems: A key component for constructing stable, well-defined liposomes with tailored membrane fluidity and permeability for targeted therapeutic delivery.
  • Biomembrane & Biophysics Research: Used to create asymmetric or specific-composition model membranes (e.g., vesicles, supported lipid bilayers) for studying membrane structure, fusion, and protein-lipid interactions.
  • Pharmaceutical Excipient Development: Serves as a critical raw material in the development of novel lipid-based excipients for enhancing drug solubility and bioavailability.
  • Diagnostic Reagents: Employed in the formulation of lipid components for diagnostic assays, sensors, and imaging contrast agents.
  • Cell Culture & Biotechnology: Used as a supplement in serum-free media or for creating specialized lipid environments in cell culture applications.
  • Cosmetic & Dermal Formulations: Incorporated into high-end cosmetic products as a biomimetic lipid to improve skin barrier function and delivery of active ingredients.

Basic Information

Product Name 1-Stearoyl-3-Myristoyl-Glycero-2-Phosphocholine
CAS No. 74838-88-3
Molecular Formula C45H90NO8P
Molecular Weight 804.18 g/mol
Synonyms 1-Stearoyl-2-myristoyl-sn-glycero-3-phosphocholine; 18:0-14:0 PC; S-M PC; 1-Octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine; Phosphatidylcholine (18:0/14:0); PC(18:0/14:0); SMPC; 1-Stearoyl-2-myristoylphosphatidylcholine
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Quality Control

Every batch of 1-Stearoyl-3-Myristoyl-Glycero-2-Phosphocholine is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We ensure compliance with stringent internal specifications for identity, purity, and acyl chain composition. A detailed Certificate of Analysis (COA) providing HPLC purity, NMR structural confirmation, and critical lipid profile data is supplied with each shipment to guarantee reproducibility and reliability for your most sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Solvent Content (Residual Solvents) Meets ICH guidelines
Acyl Chain Composition Conforms to specified ratio (18:0 / 14:0)
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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