Description

2-Fluoro-Araatp is a specialized fluorinated nucleoside analog with significant research and development applications. This compound is valued for its role as a key intermediate in the synthesis of novel antiviral and anticancer agents, where its fluorine atom can enhance metabolic stability and binding affinity. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of experimental antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to investigate the impact of fluorination on drug potency and pharmacokinetics.
• Biochemical Probes: Serves as a tool compound for studying enzyme mechanisms, particularly those involving nucleoside kinases and polymerases.
• Antiviral Agent Development: Investigated for potential activity against a range of viral targets due to its modified sugar moiety.
• Labeled Compound Synthesis: Can be used as a precursor for the preparation of isotopically labeled compounds for metabolic tracing studies.

Basic Information

Product Name	2-Fluoro-Araatp
CAS No.	74832-57-8
Molecular Formula	C10H12FN5O12P3
Molecular Weight	529.15 g/mol
Synonyms	2'-Fluoro-9-β-D-arabinofuranosyladenine 5'-triphosphate; 2-F-ara-ATP; 2-Fluoro-arabinofuranosyladenine triphosphate; 2-F-AraATP; 2-Fluoroadenine arabinoside triphosphate; 9-(2-Fluoro-β-D-arabinofuranosyl)adenine 5'-triphosphate; Fludarabine triphosphate analog
EINECS	Contact for details

Quality Control

Our 2-Fluoro-Araatp is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.