Description

4'-Methylnicotine CAS NO 74805-00-8 is a specialized nicotine derivative, a key intermediate in advanced organic synthesis and pharmaceutical research. This compound matters for its role in developing novel chemical entities and as a structural analog for studying nicotinic acetylcholine receptor interactions. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on neuropharmacology, agrochemicals, and alkaloid chemistry.

Application

• Pharmaceutical Research: A crucial intermediate in the synthesis of novel nicotinic receptor ligands and potential therapeutic agents.
• Chemical Synthesis: Serves as a building block for creating complex alkaloid derivatives and specialty organic compounds.
• Life Science Research: Used as a reference standard and probe in biochemical studies of nicotinic acetylcholine receptor (nAChR) function and structure-activity relationships (SAR).
• Agrochemical Development: Investigated as a precursor for novel plant protection agents and insecticides.
• Metabolite Studies: Employed in analytical research for the identification and quantification of nicotine-related metabolites.

Basic Information

Item	Details
Product Name	4'-Methylnicotine
CAS No.	74805-00-8
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	4'-Methylnicotine; 1-Methyl-5-(3-pyridyl)-2-pyrrolidinone (tautomeric form); 3-(1-Methyl-2-pyrrolidinyl)pyridine, 4'-methyl derivative; 4'-Methyl-3-(1-methyl-2-pyrrolidinyl)pyridine; Nicotine, 4'-methyl-; 4'-Methyl-3-(2-(N-methylpyrrolidinyl))pyridine
EINECS	Contact for details

Quality Control

Our 4'-Methylnicotine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and relevant specifications is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.