Description

n-(4-(4-Azidophenylazo)Benzoyl)-11-Aminoundecyl-N'-Oxysuccinimide Ester is a specialized heterobifunctional crosslinking reagent designed for advanced bioconjugation and surface functionalization. This compound matters for its unique dual functionality, combining a photoactivatable aryl azide group with an amine-reactive N-hydroxysuccinimide (NHS) ester, enabling controlled, two-step conjugation strategies under mild conditions. It is primarily needed by researchers and manufacturers in the fields of biopharmaceutical development, proteomics, and advanced materials science for creating stable, site-specific linkages between biomolecules and various substrates.

Application

• Bioconjugation and Protein Labeling: For covalently attaching proteins, antibodies, or peptides to surfaces, nanoparticles, or other biomolecules via a light-induced crosslinking step.
• Surface Immobilization and Biochip Fabrication: Used to functionalize glass, gold, or polymer surfaces with biomolecular probes for biosensor and microarray development.
• Affinity Chromatography Ligand Coupling: Enables the stable immobilization of ligands onto solid supports for purification resins.
• Polymer and Hydrogel Modification: Incorporates bioactive molecules into synthetic polymers or hydrogels to create smart biomaterials.
• Diagnostic Assay Development: Serves as a key reagent in the development of ELISA, lateral flow assays, and other diagnostic platforms requiring stable conjugates.
• Proteomics Research: Facilitates the study of protein-protein interactions and complex formation through photo-crosslinking.

Basic Information

Product Name	n-(4-(4-Azidophenylazo)Benzoyl)-11-Aminoundecyl-N'-Oxysuccinimide Ester
CAS No.	74726-33-3
Molecular Formula	C30H30N6O5
Molecular Weight	554.60 g/mol
Synonyms	4-((4-Azidophenyl)diazenyl)benzoic acid 11-((2,5-dioxopyrrolidin-1-yl)oxy)-11-oxoundecyl ester; Heterobifunctional Crosslinker, NHS-Azide; NHS-PEG11-Azide (Aryl Azide); Aryl Azide NHS Ester; Photoactivatable NHS Ester; 11-Aminoundecyl-NHS-Azide; N-Succinimidyl 4-((4-azidophenyl)diazenyl)benzoate, 11-aminoundecyl ester; Bioconjugation Reagent 74726-33-3
EINECS	Contact for details

Quality Control

Our n-(4-(4-Azidophenylazo)Benzoyl)-11-Aminoundecyl-N'-Oxysuccinimide Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and functional group activity are available upon request to support your research and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term stability, store under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Orange to red solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF, acetonitrile
Water Content (KF)	≤ 1.0%
Functional Activity	Confirmed by conjugation test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.