Description

Poly(I,8-Azidoi).Poly(C) CAS NO 74721-51-0 is a synthetic polynucleotide analog designed for advanced biochemical research and development. This compound is valued for its unique azido-functionalized structure, which enables specific bioconjugation and labeling applications in complex molecular systems. It is primarily utilized by researchers and developers in the fields of pharmaceutical discovery, molecular diagnostics, and materials science to create novel probes and functionalized biomaterials.

Application

• Bioconjugation and Probe Development: Acts as a key reagent for click chemistry, enabling the site-specific labeling of oligonucleotides, proteins, and other biomolecules for tracking and detection.
• Nucleic Acid Research: Used in the study of nucleic acid structure, function, and interactions, particularly where chemical modification is required.
• Diagnostic Assay Development: Serves as a component in the creation of sensitive and specific diagnostic assays, including fluorescence in situ hybridization (FISH) and PCR-based methods.
• Therapeutic Candidate Screening: Employed in high-throughput screening platforms to identify and characterize potential therapeutic agents that interact with nucleic acid targets.
• Biomaterials Engineering: Incorporated into the design of functionalized surfaces and scaffolds for biosensing, tissue engineering, and controlled drug delivery systems.
• Academic and Industrial R&D: A critical tool for fundamental research in biochemistry, molecular biology, and chemical biology across academic institutions and biotech companies.

Basic Information

Product Name	Poly(I,8-Azidoi).Poly(C)
CAS No.	74721-51-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Poly(8-azidoinosinic acid).polycytidylic acid; Poly(I8N3).Poly(C); 8-Azido-Inosine Cytosine Polynucleotide Complex; Azido-functionalized Poly(I).Poly(C); Poly(8-azidoinosine).Polycytidine; 8-N3-Poly(I):Poly(C); Clickable Poly(I):Poly(C) analog
EINECS	Contact for details

Quality Control

Our Poly(I,8-Azidoi).Poly(C) is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, spectroscopic identification (UV, IR), and functional activity verification to ensure consistency and performance for critical research applications. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or lyophilized powder
Identification (UV)	Complies
Identification (IR)	Complies
Purity (HPLC)	≥ 95%
Azido Functionalization	≥ 85% of bases modified
Solubility	Soluble in aqueous buffers, DMSO
Endotoxin Level	< 10 EU/mg (if applicable)
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.