Description

3-Methoxy Dopamine-D4 Hydrochloride is a deuterated isotopologue of the dopamine derivative 3-Methoxy Dopamine, where four hydrogen atoms are replaced by deuterium, making it a valuable internal standard for analytical chemistry. This high-purity reference material is essential for ensuring accurate quantification and method validation in sensitive mass spectrometry applications. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and contract research organizations (CROs) engaged in neurochemical analysis, pharmacokinetic studies, and the development of diagnostic assays.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of dopamine metabolites in complex biological matrices like plasma, urine, and cerebrospinal fluid.
• Pharmacokinetic and Metabolite Studies: Used in ADME (Absorption, Distribution, Metabolism, Excretion) research to track the fate of dopamine-related compounds.
• Biomarker Research: Enables accurate measurement of 3-methoxytyramine and related catecholamine metabolites in clinical and preclinical studies.
• Method Development and Validation: Serves as a stable, non-interfering standard to establish robust analytical protocols in compliance with GLP guidelines.
• Neurochemical Research: Supports investigations into dopamine metabolism, neurotransmission, and related neurological disorders.
• Quality Control in Pharmaceutical Manufacturing: Used to monitor the purity and stability of active pharmaceutical ingredients (APIs) and formulations targeting the dopaminergic system.

Basic Information

Product Name	3-Methoxy Dopamine-D4 Hydrochloride
CAS No.	74719-64-5
Molecular Formula	C9H9D4ClNO2
Molecular Weight	203.69 g/mol
Synonyms	3-Methoxytyramine-D4 Hydrochloride; 4-(2-Aminoethyl)-2-methoxyphenol-D4 Hydrochloride; 2-(3-Methoxy-4-hydroxyphenyl)ethylamine-D4 Hydrochloride; 3-O-Methyldopamine-D4 HCl; 3-OMe-DA-D4 HCl; 3-MT-D4 HCl; Deuterated 3-Methoxy Dopamine HCl
EINECS	Contact for details

Quality Control

Our 3-Methoxy Dopamine-D4 Hydrochloride is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment (D4), and impurity profiles. We support research and development requiring traceable and reliable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive); desiccants are recommended for long-term storage. Keep container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.