Description

Atp γ-(4-(n-(2-Hydroxyethyl)-n-Methylamino)Benzylamide) is a specialized biochemical derivative of adenosine triphosphate (ATP) featuring a modified γ-phosphate group. This structural modification is critical for its role as a potent and selective substrate or inhibitor in enzymatic studies, particularly for kinases and ATPases. It is primarily utilized by research institutions and pharmaceutical companies engaged in signal transduction research, high-throughput screening, and drug discovery programs targeting metabolic and cellular regulatory pathways.

Application

• Biochemical Research: As a key substrate for studying the kinetics and specificity of ATP-dependent enzymes, including protein kinases and ATP-binding cassette (ABC) transporters.
• Pharmaceutical Development: Used in assay development for screening potential therapeutic compounds that modulate ATP-utilizing enzymes in disease pathways.
• Enzymology Studies: Investigation of enzyme mechanisms, particularly those involving phosphate transfer reactions, due to its modified γ-phosphate moiety.
• Diagnostic Reagent Manufacturing: Potential component in the formulation of specialized diagnostic kits for cellular energy metabolism assays.
• Cell Signaling & Metabolic Pathway Analysis: A tool for probing intracellular signaling cascades and energy homeostasis in model cell systems.

Basic Information

Product Name	Atp γ-(4-(n-(2-Hydroxyethyl)-n-Methylamino)Benzylamide)
CAS No.	74536-50-8
Molecular Formula	C₁₉H₂₇N₆O₁₃P₃
Molecular Weight	664.41 g/mol
Synonyms	ATP-γ-[4-[N-(2-Hydroxyethyl)-N-methylamino]benzylamide]; Adenosine 5'-(γ-[4-[N-(2-Hydroxyethyl)-N-methylamino]benzyl] triphosphate); ATP-γ-AB; γ-(4-(N-(2-Hydroxyethyl)-N-methylamino)benzylamido) ATP; Modified ATP analogue; ATP benzylamide derivative; Kinase substrate analogue; EATP-γ-AB
EINECS	Contact for details

Quality Control

Our Atp γ-(4-(n-(2-Hydroxyethyl)-n-Methylamino)Benzylamide) is produced under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards to meet the exacting requirements of the life science research community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.