Description

Cortisone-4-Ara-C is a chemically modified nucleoside analog, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in the research and development of novel therapeutic agents, particularly in the fields of oncology and immunology. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the production of high-potency active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a reference standard or probe in studies investigating nucleoside metabolism, enzyme inhibition, and cellular signaling pathways.
• Antiviral Drug Development: Serves as a precursor in the research of modified cytarabine analogs with potential enhanced efficacy or reduced side effects.
• Oncology Research: Employed in the development of targeted chemotherapeutic agents that interfere with DNA synthesis in rapidly dividing cells.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Academic Research: A valuable compound for universities and research institutes exploring novel nucleoside chemistry and its biological applications.

Basic Information

Item	Details
Product Name	Cortisone-4-Ara-C
CAS No.	74517-56-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-(Cortison-21-yl)-1-β-D-arabinofuranosylcytosine; Cortison-21-yl Ara-C; 1-β-D-Arabinofuranosylcytosine, 4-(cortison-21-yl)-; Ara-C Cortisone Derivative; Cytarabine Cortisone Ester; Cortisone Cytarabine Conjugate
EINECS	Contact for details

Quality Control

Our Cortisone-4-Ara-C is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.