Description

Colchifoline is a bioactive alkaloid compound derived from plants of the genus *Colchicum*. This specialized phytochemical serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the study of anti-inflammatory agents, gout treatments, and novel therapeutic pathways. Our supply ensures high purity and batch-to-batch consistency, which are essential for reliable experimental and production outcomes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced anti-inflammatory and anti-gout medications.
• Biochemical Research: Used as a precise reference standard in pharmacokinetic and metabolic pathway studies.
• Analytical Chemistry: Employed as a high-purity calibrant in HPLC, LC-MS, and other chromatographic methods for quality control.
• Academic Research: Facilitates studies in natural product chemistry, alkaloid biosynthesis, and structure-activity relationship (SAR) analysis.
• Preclinical Development: Utilized in the formulation and testing of new drug candidates targeting microtubule dynamics.

Basic Information

Product Name	Colchifoline
CAS No.	74515-40-5
Molecular Formula	C27H31NO7
Molecular Weight	481.54 g/mol
Synonyms	Colchifoline; (-)-Colchifoline; NSC 510463; Colchicoside aglycone derivative; 3-Demethylcolchicine; 2,3,10-Trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl acetate
EINECS	Contact for details

Quality Control

Every batch of Colchifoline is manufactured and analyzed under strict quality management protocols to ensure it meets the high standards required for research and pharmaceutical applications. Our products undergo rigorous identity, purity, and impurity profile testing using advanced analytical techniques such as HPLC and NMR. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.