Description

1-o-Octadecyl-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid derivative, specifically a saturated ether-linked phosphatidylcholine analog. This compound is a critical building block in advanced lipid research and formulation, valued for its structural stability and role in mimicking biological membranes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors developing liposomal drug delivery systems, lipid nanoparticles (LNPs), and model membrane studies.

Application

• Liposomal Drug Delivery: A key lipid component for constructing stable, long-circulating liposomes for targeted therapeutic delivery.
• Lipid Nanoparticle (LNP) Formulation: Used in the development of LNPs for mRNA and other nucleic acid-based vaccines and therapies.
• Biomimetic Membrane Models: Serves as a stable, non-hydrolyzable phospholipid for creating artificial membranes in biophysical and biochemical research.
• Cell Biology & Signaling Studies: Employed to investigate lipid raft domains, membrane fluidity, and cell signaling pathways.
• Diagnostic Reagent Development: Utilized in the formulation of lipid-based reagents for diagnostic assays and imaging.
• Cosmetic & Dermal Formulations: Incorporated into advanced cosmetic products for its emulsifying and skin-barrier enhancing properties.

Basic Information

Product Name	1-o-Octadecyl-Sn-Glycero-3-Phosphocholine
CAS No.	74430-89-0
Molecular Formula	C₂₆H₅₆NO₆P
Molecular Weight	509.70 g/mol
Synonyms	1-O-Octadecyl-2-hydroxy-sn-glycero-3-phosphocholine; C18 Lyso Platelet-Activating Factor (C18 Lyso PAF); 1-O-Stearyl-2-lyso-sn-glycero-3-phosphocholine; Octadecyl lysophosphatidylcholine; ALPC (Alkyl Lysophosphatidylcholine); 1-Stearyl-2-lyso-PC; sn-Glycero-3-phosphocholine, 1-octadecyl ether; Ether-linked LysoPC C18:0
EINECS	Contact for details

Quality Control

Our 1-o-Octadecyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and formulation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol, ethanol; forms micelles in water
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.