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L-Beta,γ-Dipalmitoyl-α-Phosphatidic Acid Disodium Salt CAS NO 74427-52-4


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CAS No.:74427-52-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-Beta,γ-Dipalmitoyl-α-Phosphatidic Acid Disodium Salt is a high-purity, synthetic phospholipid derivative, specifically a disodium salt of phosphatidic acid. This compound is a critical building block in advanced lipid research and formulation, valued for its defined structure and consistent quality. It is essential for researchers and manufacturers in the pharmaceutical, cosmetic, and biotechnology sectors who require precise lipid components for drug delivery systems, biomembrane studies, and high-performance cosmetic actives.

Application

  • Liposome & Nanoparticle Formulation: A key anionic lipid component for constructing stable liposomes and lipid nanoparticles (LNPs) used in drug and gene delivery.
  • Biomembrane & Model System Research: Used to study membrane biophysics, lipid-protein interactions, and signal transduction pathways involving phosphatidic acid.
  • Cosmetic & Dermal Delivery Systems: Incorporated into advanced cosmetic formulations as a skin-identical lipid to enhance barrier function and act as a carrier for active ingredients.
  • Biochemical Reagent: Serves as a substrate or standard in enzymatic assays for phospholipases and lipid kinases.
  • Cell Culture & Media Supplements: Used in specialized cell culture applications to modulate cell signaling and membrane properties.
  • Excipient in Pharmaceutical Preparations: Potential use as a functional excipient to modify the physical properties of dosage forms.

Basic Information

Item Detail
Product Name L-Beta,γ-Dipalmitoyl-α-Phosphatidic Acid Disodium Salt
CAS No. 74427-52-4
Molecular Formula C35H66Na2O8P
Molecular Weight 706.85 g/mol
Synonyms 1,2-Dipalmitoyl-sn-glycero-3-phosphate (sodium salt); PA(16:0/16:0) sodium salt; Phosphatidic Acid (dipalmitoyl, sodium salt); DPPA, sodium salt; 3-sn-Phosphatidic acid, 1,2-dihexadecanoyl-, sodium salt; L-α-Phosphatidic acid, dipalmitoyl-, disodium salt; 1,2-Dihexadecanoyl-rac-glycero-3-phosphate disodium salt
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Quality Control

Every batch of our L-Beta,γ-Dipalmitoyl-α-Phosphatidic Acid Disodium Salt is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research and cGMP-grade applications. A Certificate of Analysis (COA) detailing specifications such as assay, impurity profile, and residual solvents is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Purity (TLC) Single major spot
Water Content (KF) ≤ 3.0%
Solvent Residues (GC) Meets ICH guidelines
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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