Description

Platelet Activating Factor-16 (PAF-16) is a synthetic, biologically active phospholipid analog that serves as a potent and specific agonist for the PAF receptor. This compound is a critical research tool for studying signal transduction pathways, inflammatory responses, and platelet aggregation mechanisms. It is essential for researchers and developers in pharmaceutical discovery, cardiovascular research, and immunology who require high-purity biochemicals to ensure experimental reproducibility and data integrity.

Application

• Biochemical Research: Used as a standard agonist in receptor binding assays and signal transduction studies to investigate the PAF pathway.
• Inflammation Models: Employed in vitro and in vivo to induce and study inflammatory responses, cytokine release, and leukocyte activation.
• Cardiovascular Studies: Applied in research on platelet aggregation, thrombosis, and vascular permeability.
• Drug Discovery & Screening: Serves as a key pharmacological tool for the development and evaluation of PAF receptor antagonists as potential therapeutics.
• Cell Biology: Utilized to study cellular activation, apoptosis, and other PAF-mediated physiological and pathological processes.
• Academic & Institutional Research: A fundamental reagent for universities and research institutes focusing on lipid mediators and their role in disease.

Basic Information

Product Name	Platelet Activating Factor-16
CAS No.	74389-68-7
Molecular Formula	C26H54NO7P
Molecular Weight	523.68 g/mol
Synonyms	PAF-16; 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; C16-PAF; AGEPC (1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine); Platelet-Activating Factor, C16; Hexadecyl PAF; PAF C-16; (R)-2-(Acetyloxy)-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
EINECS	Contact for details

Quality Control

Our Platelet Activating Factor-16 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is easily oxidized; solutions should be prepared under an inert atmosphere and used immediately. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, ethanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.