Description

Man5Glcnac is a high-purity, synthetic oligosaccharide widely used as a critical intermediate and reference standard in glycobiology research and biopharmaceutical development. Its precise structure makes it an essential tool for studying and engineering glycosylation pathways, which are vital for protein function, stability, and therapeutic efficacy. This compound is particularly valuable for researchers and manufacturers in the biotechnology and pharmaceutical industries focused on monoclonal antibodies, recombinant proteins, and advanced glycoconjugate vaccines.

Application

• Glycobiology Research: Serves as a key substrate or inhibitor for studying the activity and specificity of glycosyltransferases, glycosidases, and lectins.
• Biopharmaceutical Development: Used as a reference standard for the analysis and quality control of glycosylation patterns on therapeutic proteins, such as monoclonal antibodies.
• Enzyme Characterization: Essential for kinetic studies and mechanistic investigations of enzymes involved in N-linked glycan biosynthesis and processing.
• Diagnostic Reagent Manufacturing: Employed in the production of components for diagnostic assays that detect specific glycan-binding proteins or antibodies.
• Synthetic Chemistry Intermediate: Acts as a building block for the chemical and enzymatic synthesis of more complex oligosaccharides and glycoconjugates.
• Cell Biology Studies: Used to probe glycan-mediated cell signaling, adhesion, and recognition processes.

Basic Information

Product Name	Man5Glcnac
CAS No.	74385-50-5
Molecular Formula	C41H69N3O31
Molecular Weight	1123.98 g/mol
Synonyms	Mannose5 N-Acetylglucosamine; (Man)5(GlcNAc)1; Penta-mannosyl N-acetylglucosamine; High-mannose type oligosaccharide Man5; Manα1-6(Manα1-3)Manα1-6(Manα1-3)Manβ1-4GlcNAc; Glycan intermediate Man5GlcNAc; Oligomannose 5; D-Manp-(1-6)-[D-Manp-(1-3)]-D-Manp-(1-6)-[D-Manp-(1-3)]-D-Manp-(1-4)-D-GlcpNAc
EINECS	Contact for details

Quality Control

Our Man5Glcnac is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines for analytical characterization to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Bacterial Endotoxins	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.