Description

Z-Lys-Pro-4Mβna CAS NO 74305-53-6 is a specialized synthetic peptide derivative, widely utilized as a chromogenic substrate for the detection and study of enzyme activity. This compound is critical for researchers and manufacturers requiring precise biochemical tools for diagnostic and analytical applications. It is primarily needed by the pharmaceutical, biotechnology, and diagnostic reagent industries for enzyme kinetics research, assay development, and high-throughput screening.

Application

• Enzyme Substrate for Protease Research: Specifically designed as a selective substrate for various proteolytic enzymes, including dipeptidyl peptidases and related serine proteases.
• Biochemical Assay Development: Used in the formulation of colorimetric and fluorometric assays to measure enzyme concentration and activity in research and diagnostic kits.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential enzyme inhibitors for drug discovery programs.
• Diagnostic Reagent Manufacturing: A key component in the production of clinical diagnostic reagents for detecting specific enzyme markers related to physiological and pathological conditions.
• Academic & Industrial R&D: Serves as a fundamental tool in university and corporate laboratories for studying enzyme mechanisms, kinetics, and specificity.
• Quality Control in Bioprocessing: Applied in monitoring the activity of enzymes used in biotechnological manufacturing processes to ensure batch consistency and product quality.

Basic Information

Item	Detail
Product Name	Z-Lys-Pro-4Mβna
CAS No.	74305-53-6
Molecular Formula	C₂₈H₃₆N₄O₇
Molecular Weight	540.61 g/mol
Synonyms	Z-Lys-Pro-4-Methoxy-β-naphthylamide; N-Benzyloxycarbonyl-L-lysyl-L-proline 4-methoxy-2-naphthylamide; Z-Lys-Pro-4-Methoxy-2-naphthylamide; Boc-Lys-Pro-4MβNA (common abbreviation); L-Lysyl-L-proline 4-methoxy-β-naphthylamide, N-[(phenylmethoxy)carbonyl]-; Chromogenic Substrate for DPP IV; DPP IV Substrate; Validity® Substrate (trade name context); Peptide chromogenic substrate 74305-53-6
EINECS	Contact for details

Quality Control

Every batch of Z-Lys-Pro-4Mβna is produced under strict quality management protocols. We ensure compliance with high-purity standards suitable for research and diagnostic applications. Comprehensive testing includes identity confirmation, purity assessment, and impurity profiling. Certificates of Analysis (COA) detailing lot-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term stability, consider storage at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.