Description

1-(5'-Oxohexylcarbamoyl)-5-Fluorouracil is a specialized fluorouracil derivative, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in creating targeted chemotherapeutic agents and other bioactive molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel anticancer drugs and other therapeutic compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel fluoropyrimidine-based anticancer agents and prodrugs.
• Anticancer Research: Used in biochemical and pharmacological research to study structure-activity relationships and develop new therapeutic candidates.
• Prodrug Development: Serves as a precursor molecule in the design of prodrugs aimed at improving drug targeting and reducing systemic toxicity.
• Organic Synthesis: Employed in specialized organic synthesis for introducing the fluorouracil moiety into more complex molecular architectures.
• Bioconjugation Studies: Utilized in research exploring the conjugation of active pharmaceutical ingredients to carriers or targeting ligands.

Basic Information

Product Name	1-(5'-Oxohexylcarbamoyl)-5-Fluorouracil
CAS No.	74173-51-6
Molecular Formula	C11H14FN3O4
Molecular Weight	271.25 g/mol
Synonyms	5-Fluoro-1-[(5-oxohexyl)carbamoyl]uracil; 1-(5-Oxohexylcarbamoyl)-5-fluorouracil; 5-Fluorouracil-1-(5-oxohexylcarboxamide); 1H-Pyrimidine-2,4-dione, 5-fluoro-1-[[(5-oxohexyl)amino]carbonyl]-; 5-FU derivative with 5-oxohexylcarbamoyl moiety; N-(5-Oxohexyl)-5-fluorouracil-1-carboxamide
EINECS	Contact for details

Quality Control

Our 1-(5'-Oxohexylcarbamoyl)-5-Fluorouracil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.