Description

2,3-Dihydro-2-(Iodoacetyl)-3-Methylphthalazine-1,4-Dione is a specialized heterocyclic building block and chemical intermediate of significant interest in advanced organic synthesis. Its core value lies in the reactive iodoacetyl moiety, which serves as a versatile handle for selective alkylation and conjugation reactions under mild conditions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in medicinal chemistry programs and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in programs targeting enzyme inhibition.
• Bioconjugation Reagent: Used for the selective labeling and modification of proteins, peptides, and other biomolecules via reaction with thiol groups.
• Agrochemical Synthesis: Intermediate in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Precursor for creating functionalized polymers or small molecules with specific electronic or photophysical properties.
• Chemical Biology Probes: Employed in the design of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Cross-linking Agent: Potential use in creating covalent cross-links between molecules in biochemical and materials applications.

Basic Information

Product Name	2,3-Dihydro-2-(Iodoacetyl)-3-Methylphthalazine-1,4-Dione
CAS No.	73972-89-1
Molecular Formula	C₁₁H₉IN₂O₃
Molecular Weight	344.11 g/mol
Synonyms	2-(Iodoacetyl)-3-methyl-2,3-dihydrophthalazine-1,4-dione; 3-Methyl-2,3-dihydro-2-(iodoacetyl)phthalazine-1,4-dione; 2-(Iodoacetyl)-3-methylphthalhydrazide; N-Iodoacetyl-3-methylphthalhydrazide; Iodoacetyl Methylphthalhydrazide; Phthalazine-1,4-dione, 2,3-dihydro-2-(iodoacetyl)-3-methyl-
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dihydro-2-(Iodoacetyl)-3-Methylphthalazine-1,4-Dione is produced and tested under a strict quality management system to ensure consistency and reliability for your critical research and development work. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.