Description

Trisialosyllactosylceramide CAS NO 73904-48-0 is a complex glycosphingolipid, specifically a ganglioside, characterized by its three sialic acid residues attached to a lactosylceramide core. This compound is of significant interest in biochemical and biomedical research due to its role as a specific cell surface antigen and its involvement in cellular recognition and signaling processes. It is primarily utilized by research institutions and pharmaceutical developers focused on immunology, oncology, and neuroscience for studying cell membrane dynamics, developing diagnostic tools, and exploring therapeutic targets.

Application

• Biomedical Research: Used as a standard or reagent in studies investigating ganglioside function, cell adhesion, and signal transduction pathways.
• Immunological Studies: Serves as a specific antigen for the production and characterization of monoclonal antibodies in autoimmune and cancer research.
• Neuroscience Research: Employed in exploring the role of complex gangliosides in neural development, synaptic function, and neurodegenerative diseases.
• Diagnostic Development: Acts as a critical component in the development of immunoassays and biosensors for detecting specific antibodies or biomarkers.
• Pharmaceutical R&D: Utilized as a reference compound in drug discovery programs targeting glycolipid-mediated diseases and in vaccine adjuvant research.
• Cell Biology: Applied in membrane biophysics studies to understand lipid raft composition and function.

Basic Information

Product Name	Trisialosyllactosylceramide
CAS No.	73904-48-0
Molecular Formula	C110H187N5O48
Molecular Weight	~2371.7 g/mol
Synonyms	Ganglioside GT3; GT3 Ganglioside; II3(NeuAc)3-LacCer; Lactosylceramide trisialoside; Trisialosyl-lactosylceramide; NeuAcα2-8NeuAcα2-8NeuAcα2-3Galβ1-4Glcβ1-1'Cer; 2-O-(N-Acetyl-α-neuraminosyl)-2-O-(N-acetyl-α-neuraminosyl)-2-O-(N-acetyl-α-neuraminosyl)-O-β-D-galactopyranosyl-(1→4)-O-β-D-glucopyranosylceramide
EINECS	Contact for details

Quality Control

Our Trisialosyllactosylceramide is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for critical research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as purity, identity, and moisture content.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in Chloroform/Methanol/Water mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.