Description

7-o-Demethylisothalicberine is a specialized isoquinoline alkaloid of significant interest in advanced chemical research and development. This compound serves as a crucial intermediate and reference standard for the synthesis and analysis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on alkaloid chemistry and drug discovery programs.

Application

• Pharmaceutical Research Intermediate: A key building block for the synthesis of novel alkaloid-based therapeutic agents.
• Biochemical Reference Standard: Used for analytical method development, calibration, and quality control in laboratories studying isoquinoline compounds.
• Academic & Discovery Chemistry: Employed in structure-activity relationship (SAR) studies and pharmacological screening assays.
• Natural Product Synthesis: A critical precursor in the semi-synthesis or total synthesis of complex natural products.
• Analytical Chemistry: Serves as a high-purity standard for chromatographic techniques like HPLC and LC-MS in compound identification and purity assessment.

Basic Information

Product Name	7-o-Demethylisothalicberine
CAS No.	73711-14-5
Molecular Formula	C19H21NO4
Molecular Weight	327.37 g/mol
Synonyms	7-O-Demethylisothalicberine; Isothalicberine, 7-O-demethyl-; 7-Desmethylisothalicberine; 1,2,3,10-Tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline; (6aS)-1,2,3,10-Tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
EINECS	Contact for details

Quality Control

Our 7-o-Demethylisothalicberine is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.