Description

Arylazido-β-Alanyl-Nadp is a specialized biochemical reagent and a photoaffinity labeling derivative of the essential coenzyme NADP+. This compound matters because it serves as a critical tool for researchers investigating enzyme active sites, protein-ligand interactions, and metabolic pathways through covalent crosslinking initiated by UV light. It is primarily needed by scientists and manufacturers in pharmaceutical R&D, biochemical research, and enzymology for probing complex biological systems.

Application

• Photoaffinity Labeling Studies: Used to covalently tag and identify binding sites of NADP+-dependent enzymes, such as dehydrogenases and reductases.
• Enzyme Mechanism Research: Essential for elucidating the structure and function of active sites in metabolic enzymes.
• Proteomics and Target Identification: Aids in the discovery and validation of protein targets in drug development pipelines.
• Bioconjugation and Probe Development: Serves as a key intermediate for synthesizing advanced molecular probes and diagnostic tools.
• Metabolic Pathway Analysis: Employed to study and map NADP+-involved pathways in cellular metabolism.

Basic Information

Product Name	Arylazido-β-Alanyl-Nadp
CAS No.	73617-93-3
Molecular Formula	C27H33N8O17P3
Molecular Weight	858.52 g/mol
Synonyms	4-Azido-2-nitrophenyl-β-alanyl-NADP; β-Alanyl-NADP, 4-azido-2-nitrophenyl-; Arylazido-β-alanyl NADP; 4-Azido-2-nitrophenyl-β-alanyl NADP; Photoaffinity NADP+; NADP+ photoaffinity label; 4-Azido-2-nitrophenyl-β-alanyl nicotinamide adenine dinucleotide phosphate; Arylazido-β-alanyl NADP+
EINECS	Contact for details

Quality Control

Our Arylazido-β-Alanyl-Nadp is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dark, dry place before opening to minimize condensation and degradation.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.