Description

Suc-Ala-Ala-Ala-Amc CAS NO 73617-90-0 is a specialized fluorogenic peptide substrate designed for the sensitive detection and quantification of protease activity. This compound is critical for biochemical research and pharmaceutical development, enabling precise enzymatic studies. It is primarily utilized by researchers and quality control laboratories in the life sciences, biotechnology, and pharmaceutical industries.

Application

• Protease Enzyme Assays: A key fluorogenic substrate for kinetic studies and high-throughput screening (HTS) of serine proteases, including chymotrypsin and subtilisin.
• Drug Discovery & Development: Used to screen and evaluate the efficacy and potency of novel protease inhibitor candidates in pharmaceutical R&D.
• Biochemical Research: Essential tool for investigating protease mechanisms, specificity, and regulation in academic and industrial research settings.
• Diagnostic Reagent Manufacturing: Serves as a core component in the formulation of diagnostic kits for detecting specific protease biomarkers.
• Quality Control in Biologics: Employed to monitor and validate the activity and consistency of enzyme-based biopharmaceutical products during production.

Basic Information

Product Name	Suc-Ala-Ala-Ala-Amc
CAS No.	73617-90-0
Molecular Formula	C23H30N4O8
Molecular Weight	490.51 g/mol
Synonyms	Succinyl-Ala-Ala-Ala-7-amido-4-methylcoumarin; Suc-AAA-AMC; Suc-Ala-Ala-Ala-AMC; N-Succinyl-L-alanyl-L-alanyl-L-alanine 7-amido-4-methylcoumarin; Protease Substrate Suc-AAA-AMC; Fluorogenic Substrate for Chymotrypsin; AMC-labeled tri-alanine substrate; Suc-A-A-A-AMC
EINECS	Contact for details

Quality Control

Every batch of Suc-Ala-Ala-Ala-Amc is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.