Description

S-Nitroso-β-D-Thioglucose is a specialized organosulfur and nitroso compound that serves as a critical biochemical reagent. This compound is valued for its role as a nitric oxide (NO) donor and its ability to modify thiol groups, making it essential for advanced research in redox biology and cellular signaling. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for studying nitrosative stress, protein S-nitrosylation, and developing novel therapeutic pathways.

Application

• Biochemical Research: As a precise nitric oxide (NO) donor for studying NO-mediated signaling pathways and nitrosative stress in cellular models.
• Pharmaceutical Development: Used in the research and development of novel therapeutics targeting S-nitrosylation for conditions like cardiovascular disease and neurodegeneration.
• Protein Chemistry: A reagent for the selective S-nitrosylation of cysteine residues in proteins to study function, structure, and post-translational modifications.
• Enzyme Inhibition Studies: Employed to investigate the modulation of enzyme activity through thiol group modification.
• Antioxidant Research: Serves as a tool to probe cellular antioxidant defense mechanisms against reactive nitrogen species.
• Diagnostic Assay Development: Potential use in developing assays and sensors for detecting nitric oxide or nitrosothiols in biological samples.

Basic Information

Product Name	S-Nitroso-β-D-Thioglucose
CAS No.	73427-33-5
Molecular Formula	C6H11NO6S
Molecular Weight	225.22 g/mol
Synonyms	S-Nitroso-β-D-thioglucose; 1-Thio-β-D-glucose S-nitrosothiol; β-D-Glucopyranose, 1-thio-, S-nitroso-; S-Nitroso-1-thio-β-D-glucopyranose; SNOG; S-Nitrosothioglucose; Nitrosoglucose thioether; 1-Thio-β-D-glucose S-nitroso derivative
EINECS	Contact for details

Quality Control

Our S-Nitroso-β-D-Thioglucose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive and should be handled under subdued light. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in water, DMSO, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.