Description

11-Hydroperoxyeicosa-5,8,12,14-Tetraenoic Acid is a specialized polyunsaturated fatty acid hydroperoxide, a key intermediate in the lipoxygenase pathway of arachidonic acid metabolism. This compound is of significant interest for its role as a biochemical precursor in the synthesis of various eicosanoids, including leukotrienes and lipoxins, which are critical mediators in inflammatory and immune responses. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors for drug discovery, biochemical research, and the development of analytical standards.

Application

• Biochemical Research: Critical intermediate for studying the lipoxygenase pathway, enzyme kinetics, and eicosanoid biosynthesis.
• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for drug development and quality control.
• Inflammation & Immunology Studies: Serves as a precursor in the synthesis of pro-inflammatory and pro-resolving lipid mediators for cellular and in-vivo research.
• Cell Signaling Pathway Analysis: Employed to investigate oxidative stress responses and signal transduction mechanisms related to lipid peroxidation.
• Academic & Institutional Research: A vital tool for universities and research institutes exploring lipidomics, metabolomics, and related biochemical fields.

Basic Information

Product Name	11-Hydroperoxyeicosa-5,8,12,14-Tetraenoic Acid
CAS No.	73347-42-9
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	11-HPETE; 11(S)-HPETE; 11(S)-Hydroperoxy-5Z,8Z,12E,14Z-eicosatetraenoic acid; 11-Hydroperoxyeicosatetraenoic Acid; 11(S)-Hydroperoxyeicosa-5Z,8Z,12E,14Z-tetraenoic Acid; Arachidonic acid 11-hydroperoxide; 11-Hydroperoxyarachidonic acid
EINECS	Contact for details

Quality Control

Every batch of 11-Hydroperoxyeicosa-5,8,12,14-Tetraenoic Acid is produced and analyzed under strict quality management protocols to ensure identity, purity, and stability. Our analytical methods include HPLC, NMR, and mass spectrometry to verify the compound meets stringent research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and chromatographic data is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent degradation due to its easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing or reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by titration)
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.