Description

Z-Arg-Arg-4-Methoxy-2-Naphthylamine is a specialized synthetic peptide derivative designed for use as a high-sensitivity chromogenic substrate in enzymatic assays. This compound is critical for biochemical research and diagnostic applications where precise detection of protease activity is required. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic research institutions focused on enzymology and proteomics.

Application

• Protease Activity Assays: Acts as a selective chromogenic substrate for the detection and quantification of trypsin-like serine proteases, including thrombin, plasmin, and kallikrein.
• Diagnostic Development: Used in the formulation of clinical diagnostic kits for measuring blood coagulation factors and other protease-related biomarkers.
• Biochemical Research: Enables kinetic studies and inhibitor screening for proteolytic enzymes in academic and industrial research settings.
• Pharmaceutical Quality Control: Employed in purity and activity testing of biopharmaceutical products, particularly those involving recombinant proteases.
• Cell Biology Studies: Facilitates the study of protease function and signaling pathways in cellular systems.

Basic Information

Product Name	Z-Arg-Arg-4-Methoxy-2-Naphthylamine
CAS No.	73167-98-3
Molecular Formula	C31H42N8O6
Molecular Weight	622.73 g/mol
Synonyms	Benzyloxycarbonyl-Arg-Arg-4-Methoxy-2-Naphthylamide; Z-Arg-Arg-4M2NA; Z-Arg-Arg-β-Naphthylamide; Z-RR-4MβNA; Chromogenic Substrate for Trypsin; Thrombin Substrate Z-RR-4MβNA; Nα-CBZ-L-arginyl-L-arginine 4-methoxy-2-naphthylamide; CBZ-Arg-Arg-4-Methoxy-β-Naphthylamide
EINECS	Contact for details

Quality Control

Our Z-Arg-Arg-4-Methoxy-2-Naphthylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and functional enzymatic assay validation. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	≥ 95% of reference standard in enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.