Description

Sodium Cholate Hydrate is the sodium salt of cholic acid, a primary bile acid. This high-purity biochemical is essential for its role as a natural, biological detergent, facilitating the solubilization and absorption of lipids and fat-soluble vitamins. It is a critical reagent in life science research, pharmaceutical development, and diagnostic applications, valued for its consistent quality and performance.

Application

• Pharmaceutical Excipient & Formulation: Used as a solubilizing agent and absorption enhancer in drug delivery systems, particularly for poorly water-soluble active pharmaceutical ingredients (APIs).
• Cell Culture & Molecular Biology: Serves as a mild, non-denaturing detergent for membrane protein isolation and solubilization in biochemical research and assay development.
• Diagnostic Reagents: A key component in the formulation of clinical diagnostic kits, including those for liver function and cholesterol testing.
• Biochemical Standard & Reference Material: Employed as a high-purity standard in analytical chemistry, chromatography, and quality control laboratories.
• Bile Acid Metabolism Research: Fundamental for in vitro and in vivo studies investigating hepatobiliary function, lipid digestion, and metabolic pathways.

Basic Information

Product Name	Sodium Cholate Hydrate
CAS No.	73163-53-8
Molecular Formula	C24H39NaO5 • xH2O
Molecular Weight	430.56 g/mol (anhydrous basis)
Synonyms	Cholic Acid Sodium Salt Hydrate; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid Sodium Salt; Sodium 3α,7α,12α-Trihydroxy-5β-cholan-24-oate; Taurocholic Acid Sodium Salt (common misnomer, verify structure); Sodium Cholate; Cholate Sodium Salt; Cholalic Acid Sodium Salt; NSC 220423
EINECS	Contact for details

Quality Control

Our Sodium Cholate Hydrate is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets stringent specifications for purity and identity. Certificates of Analysis (COA) are provided with each batch, detailing results from tests including assay, identification, and impurity profiles. We can supply material suitable for research and development, as well as grades aligned with cGMP principles for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and prevent caking.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 10.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solubility	Clear, colorless solution in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.