Description

15-Hydroperoxythromboxane A2 is a bioactive eicosanoid and a key intermediate metabolite in the arachidonic acid cascade. This compound is of significant interest for its role in studying oxidative stress pathways and inflammatory responses. It is primarily utilized by researchers and developers in the pharmaceutical and life science sectors for biochemical research, drug discovery, and as a reference standard in analytical method development.

Application

• Biochemical Research: Used as a critical intermediate to study the thromboxane pathway, lipid peroxidation, and related oxidative stress mechanisms.
• Pharmaceutical R&D: Serves as a reference standard and a tool compound in the discovery and development of anti-inflammatory and cardiovascular drugs.
• Analytical Chemistry: Employed as a high-purity standard for method validation in chromatographic techniques like HPLC and LC-MS for eicosanoid analysis.
• Enzyme Studies: Acts as a substrate for investigating the activity and inhibition of enzymes such as thromboxane synthase and peroxidases.
• Cell Signaling Research: Utilized in cellular assays to probe receptor-mediated signaling pathways and the biological effects of lipid hydroperoxides.

Basic Information

Product Name	15-Hydroperoxythromboxane A2
CAS No.	73151-69-6
Molecular Formula	C20H32O7
Molecular Weight	384.47 g/mol
Synonyms	15-HPETE; 15(S)-HPETE; 15(S)-Hydroperoxyeicosatetraenoic Acid; 15-Hydroperoxy-5,8,11,13-eicosatetraenoic Acid; (15S)-HPETE; 15(S)-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; Thromboxane A2 15-hydroperoxide; 15-Hydroperoxy Thromboxane A2
EINECS	Contact for details

Quality Control

Our 15-Hydroperoxythromboxane A2 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability data. We adhere to ISO 9001 quality management principles, and our analytical methods are validated to meet the rigorous standards required for reference materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is moisture-sensitive; ensure the container is sealed in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular structure
Purity (HPLC)	≥ 95% (Area Percent)
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.