Description

n-Acetyl-N'-(4-Glyoxylylbenzoyl)Cystamine is a specialized heterobifunctional crosslinking agent featuring both a photoreactive glyoxylyl group and a cleavable disulfide bond. This compound matters for its precise ability to create reversible, photo-inducible linkages between biomolecules, enabling advanced studies in protein-protein interactions, affinity labeling, and controlled drug delivery systems. It is primarily needed by researchers and manufacturers in the fields of bioconjugation, proteomics, pharmaceutical development, and advanced material science.

Application

• Bioconjugation and Crosslinking: For creating photo-activatable, reversible crosslinks between proteins, peptides, and other biomolecules.
• Affinity Chromatography: As a key reagent for the synthesis of photo-cleavable affinity resins and columns.
• Drug Delivery System Development: Enabling the design of stimuli-responsive (light/redox) drug carriers and prodrugs.
• Proteomics Research: Used in photo-affinity labeling to capture and study transient protein interactions.
• Surface Functionalization: For modifying surfaces with biomolecules via a cleavable linker for biosensor and microarray applications.
• Polymer Chemistry: As a building block for synthesizing smart polymers with degradable disulfide linkages.

Basic Information

Item	Detail
Product Name	n-Acetyl-N'-(4-Glyoxylylbenzoyl)Cystamine
CAS No.	73097-03-7
Molecular Formula	C15H18N2O5S2
Molecular Weight	370.44 g/mol
Synonyms	N-[2-[[2-(Acetylamino)ethyl]dithio]ethyl]-4-(oxoacetyl)benzamide; 4-Glyoxylylbenzoyl-N-acetylcystamine; N-Acetyl-S-(2-aminoethylthio)cysteamine 4-glyoxylylbenzoate; Photo-cleavable heterobifunctional crosslinker; Glyoxylylbenzoyl cystamine derivative; Acetylated Glyoxylylbenzoyl Cystamine; (4-(2-Oxoacetyl)benzoyl)-N-acetylcystamine
EINECS	Contact for details

Quality Control

Our n-Acetyl-N'-(4-Glyoxylylbenzoyl)Cystamine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and maintain stability. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.