Description

5-(Dimethylamino-1-Naphthoyl)Adenosine Triphosphate is a fluorescently labeled derivative of adenosine triphosphate (ATP), designed for high-sensitivity detection and analysis. This compound is critical for researchers and developers requiring precise, non-radioactive tracking of ATP-dependent enzymatic processes. It is primarily utilized in advanced life science research, diagnostic assay development, and pharmaceutical screening applications where visualization of energy transfer is essential.

Application

• Biochemical Research & Enzyme Kinetics: As a fluorescent substrate for real-time monitoring of ATP hydrolysis and synthesis by kinases, ATPases, and other ATP-dependent enzymes.
• Diagnostic Assay Development: A key component in the design of homogeneous, fluorescence-based assays for high-throughput screening (HTS) in drug discovery.
• Cellular Energy Metabolism Studies: Used to probe and visualize ATP levels and localization within live or fixed cells using fluorescence microscopy.
• Biosensor Fabrication: Integration into sensor platforms for the detection of enzymatic activity or for environmental monitoring of biological contaminants.
• Pharmaceutical Quality Control: Employed in potency assays for biopharmaceuticals whose mechanism of action involves ATP binding or consumption.
• Molecular Probes & Labeling: Serves as a critical reagent for labeling proteins or other biomolecules via ATP-binding domains for pull-down assays or imaging.

Basic Information

Item	Detail
Product Name	5-(Dimethylamino-1-Naphthoyl)Adenosine Triphosphate
CAS No.	72947-54-7
Molecular Formula	C23H29N6O13P3
Molecular Weight	690.43 g/mol
Synonyms	DMN-ATP; 5-(N,N-Dimethylamino-1-naphthalenesulfonamido)adenosine-5'-triphosphate; 1,5-Dansyl-ATP; Fluorescent ATP analog; ε-ATP-DMN; N6-(5-Dimethylaminonaphthalene-1-sulfonyl)adenosine-5'-triphosphate; ATP-Dansyl; 5-Dimethylaminonaphthalene-1-sulfonamidoadenosine triphosphate
EINECS	Contact for details

Quality Control

Our production of 5-(Dimethylamino-1-Naphthoyl)Adenosine Triphosphate adheres to stringent quality protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is characterized by HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities like unlabeled ATP. A comprehensive Certificate of Analysis (COA) detailing purity, fluorescence properties, and solvent content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
ATP Content (HPLC)	≤ 2%
Water Content (KF)	≤ 3%
Fluorescence Properties	Ex/Em ~340 nm / ~520 nm (solvent dependent)
Solubility	Soluble in DMSO, DMF, aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.