Description

(5-(Dimethylamino-1-Naphthoyl))Adenosine Diphosphate is a specialized, fluorescently labeled nucleotide analog crucial for biochemical research and diagnostic development. Its core value lies in its ability to act as a sensitive probe for monitoring enzymatic activity, particularly in assays involving kinases, ATPases, and other nucleotide-dependent enzymes. This compound is essential for researchers and manufacturers in the fields of life science research, high-throughput screening (HTS), and in vitro diagnostic (IVD) kit production, where precise detection of biochemical interactions is paramount.

Application

• Biochemical Assay Development: As a fluorescent substrate for kinases, ATPases, and other phosphotransferase enzymes in activity and inhibition studies.
• High-Throughput Screening (HTS): Enabling the discovery of novel drug candidates by serving as a key reagent in fluorescence-based screening assays.
• Enzyme Kinetics & Mechanism Studies: Providing a sensitive readout for real-time monitoring of enzymatic reactions and kinetic parameter determination.
• Diagnostic Kit Manufacturing: Used as a critical component in the production of research-use-only (RUO) and in vitro diagnostic (IVD) test kits for cellular signaling pathways.
• Cellular Signaling Research: Investigating intracellular energy transfer and signaling cascades involving adenosine nucleotides.
• Apoptosis & Cell Viability Assays: Acting as a probe in assays designed to measure cellular ATP levels as an indicator of metabolic health.

Basic Information

Product Name	(5-(Dimethylamino-1-Naphthoyl))Adenosine Diphosphate
CAS No.	72947-52-5
Molecular Formula	C23H27N6O12P2
Molecular Weight	650.44 g/mol
Synonyms	DAN-ADP; 5-Dimethylaminonaphthalene-1-sulfonyl-adenosine diphosphate; Dansyl-ADP; 1,5-Dansyl adenosine 5'-diphosphate; N6-(5-(Dimethylamino)naphthalene-1-sulfonyl)-adenosine-5'-diphosphate; Fluorescent ADP analog; Adenosine-5'-diphosphate, N6-[(5-dimethylamino-1-naphthalenyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our (5-(Dimethylamino-1-Naphthoyl))Adenosine Diphosphate is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and fluorescence spectroscopy for functional validation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light will degrade product performance. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Fluorescence Properties	Ex/Em ~340/520 nm (verify in buffer)
Water Content (KF)	≤ 3.0%
Biological Activity	Functional as enzyme substrate (lot-specific data provided)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.