Description

Dapiprazole is a selective α-1 adrenergic receptor antagonist, a pharmaceutical compound of significant interest in ophthalmic medicine. Its primary value lies in its ability to reverse pharmacologically induced mydriasis, making it a critical agent in clinical and surgical settings. This product is essential for pharmaceutical manufacturers, research institutions, and compounding pharmacies developing treatments for ocular conditions. We supply Dapiprazole CAS NO 72822-12-9 to the global market with a commitment to consistent quality and reliable supply chain integrity.

Application

• Ophthalmic Solutions: As the active pharmaceutical ingredient (API) in formulations designed to reverse mydriasis (pupil dilation) induced by agents like phenylephrine or tropicamide.
• Surgical Adjunct: Used in ophthalmic surgery to constrict the pupil post-procedure, aiding in recovery and reducing post-operative photophobia.
• Clinical Diagnostics: Employed in eye examinations to rapidly return the pupil to its normal size after diagnostic dilation, improving patient comfort.
• Pharmaceutical Research: Serves as a key reference standard and building block in preclinical research targeting α-adrenergic pathways.
• Drug Development: Utilized in the R&D of new therapeutic agents for glaucoma and other intraocular pressure-related disorders.
• Compounding Pharmacy: A critical raw material for specialized compounding of custom ophthalmic preparations.

Basic Information

Product Name	Dapiprazole
CAS No.	72822-12-9
Molecular Formula	C19H27N5
Molecular Weight	325.45 g/mol
Synonyms	Dapiprazole Hydrochloride (common salt form); 5,6,7,8-Tetrahydro-3-[2-[4-(2-methylphenyl)-1-piperazinyl]ethyl]-s-triazolo[4,3-a]pyridine; Glamidolo; Reve-Eyes; α-Adrenergic Blocker Dapiprazole; 1-Piperazineethanol, 4-(2-methylphenyl)-, derivative; UNII-5Q8Y6Y6J8B
EINECS	Contact for details

Quality Control

Our Dapiprazole is manufactured and tested under a strict quality management system. Each batch is subjected to comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and the absence of specified impurities. We support compliance with cGMP, ICH Q7, and other relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.