Description

Aminopropylcobalamin is a specialized organometallic compound and a structural analog of Vitamin B12 (Cobalamin). This product is significant for its role as a biochemical precursor and research tool in the study of cobalamin-dependent enzymes and metabolic pathways. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in advanced biochemical synthesis, metabolic research, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a cofactor analog in enzymatic studies to investigate the mechanisms of B12-dependent methyltransferases and isomerases.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel cobalamin-based pharmaceuticals and targeted drug delivery systems.
• Metabolic Pathway Analysis: Employed in tracer studies and metabolic engineering to understand and manipulate pathways involving propionate metabolism and one-carbon units.
• Reference Standard: Utilized as a high-purity analytical standard in HPLC and LC-MS methods for the quantification of cobalamin derivatives.
• Nutritional Science Studies: Applied in research to explore the bioavailability and novel functions of cobalamin analogs.
• Enzyme Engineering: Acts as a substrate or inhibitor in the development and optimization of industrial biocatalysts.

Basic Information

Product Name	Aminopropylcobalamin
CAS No.	72728-11-1
Molecular Formula	C₆₄H₉₁CoN₁₃O₁₄P
Molecular Weight	1404.4 g/mol
Synonyms	Vitamin B12a aminopropyl derivative; Coα-[α-(5-Aminopentyl)]-Coβ-cyanocobamide; 5'-Deoxy-5'-adenosylcobalamin aminopropyl analog; APC; Aminopropyl-B12; Adenosylcobalamin aminopropyl homolog; Cob(II)alamin aminopropyl derivative
EINECS	Contact for details

Quality Control

Our Aminopropylcobalamin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via UV-Vis and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to prevent condensation. For long-term stability, store under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Dark red crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Characteristic spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.