Description

Suc-Ala-Ala-Pro-Met-Pna CAS NO 72682-73-6 is a specialized chromogenic peptide substrate designed for enzymatic activity assays. This compound is critical for researchers and quality control laboratories requiring precise, quantitative measurement of protease and peptidase activity. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for drug discovery, enzyme characterization, and biochemical pathway analysis.

Application

• Protease and Peptidase Activity Assays: Used as a specific substrate to measure the kinetic activity of enzymes like chymotrypsin, elastase, and related serine proteases in high-throughput screening (HTS) platforms.
• Drug Discovery & Development: Essential for screening and evaluating potential enzyme inhibitors in pharmaceutical research for conditions involving proteolytic dysregulation.
• Biochemical Research: Serves as a key tool for studying enzyme mechanisms, specificity, and kinetics in academic and industrial R&D laboratories.
• Quality Control in Biologics: Employed in the QC testing of therapeutic proteins and enzymes to ensure batch-to-batch consistency and activity.
• Diagnostic Reagent Manufacturing: A component in the formulation of diagnostic kits for clinical and research use that detect specific protease activities.

Basic Information

Product Name	Suc-Ala-Ala-Pro-Met-Pna
CAS No.	72682-73-6
Molecular Formula	C27H38N6O9S
Molecular Weight	622.70 g/mol
Synonyms	N-Succinyl-Ala-Ala-Pro-Met-p-nitroanilide; Suc-AAPM-pNA; Suc-AAPM-pNA Substrate; Suc-Ala-Ala-Pro-Met-pNA; N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-methionine 4-nitroanilide; Suc-AAPM-NA; Chromogenic Substrate for Chymotrypsin; Protease Substrate 72682-73-6
EINECS	Contact for details

Quality Control

Every batch of Suc-Ala-Ala-Pro-Met-Pna is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. A detailed Certificate of Analysis (COA) documenting identity, purity (HPLC), and performance is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Conforms to reference standard in enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.