Description

Suc-Ala-Ala-Pro-Ala-Pna CAS NO 72682-69-0 is a specialized chromogenic peptide substrate designed for the sensitive detection and quantification of proteolytic enzyme activity. This compound is a critical reagent in biochemical research and diagnostic development, offering high specificity for certain serine proteases. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for enzyme kinetics studies, inhibitor screening, and assay development.

Application

• Enzyme Kinetics Research: Used as a specific substrate to study the catalytic activity, mechanism, and inhibition of target proteases like elastase and related enzymes.
• High-Throughput Screening (HTS): Employed in pharmaceutical discovery for screening libraries of compounds to identify potential protease inhibitors for therapeutic development.
• Diagnostic Assay Development: Serves as a key component in developing colorimetric or fluorometric assays for clinical diagnostics to measure protease levels in biological samples.
• Biochemical Reagent: Acts as a standard and essential reagent in research laboratories for quantifying protease activity in cell lysates, tissue extracts, and purified enzyme preparations.
• Quality Control in Biomanufacturing: Utilized to monitor and validate the activity of enzyme-based products or processes within biopharmaceutical production.

Basic Information

Product Name	Suc-Ala-Ala-Pro-Ala-Pna
CAS No.	72682-69-0
Molecular Formula	C27H38N6O9
Molecular Weight	590.63 g/mol
Synonyms	Suc-AAPF-pNA; N-Succinyl-Ala-Ala-Pro-Ala-p-nitroanilide; Suc-AAPF-pNA; Sucinyl-Ala-Ala-Pro-Ala-pNA; Suc-AAPA-pNA; N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide; Elastase Substrate IV; AAPF-pNA
EINECS	Contact for details

Quality Control

Our Suc-Ala-Ala-Pro-Ala-Pna is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods. A detailed Certificate of Analysis (COA) documenting purity, assay, and related substances is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.