Description

4-Nitrophenyl 6-o-(A-D-Mannopyranosyl)-A-D-Mannopyranoside is a specialized synthetic glycoside derivative, primarily utilized as a chromogenic substrate in enzymatic assays. Its core value lies in its ability to act as a specific substrate for α-mannosidase enzymes, enabling precise measurement of enzymatic activity in research and diagnostic applications. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors who require reliable tools for enzyme kinetics, inhibitor screening, and biochemical pathway analysis.

Application

• Enzymatic Substrate for α-Mannosidase: Serves as a critical chromogenic substrate for the detection and quantification of α-mannosidase activity in vitro.
• Biochemical Research: Used in fundamental research to study glycosidase mechanisms, enzyme kinetics, and carbohydrate metabolism.
• Diagnostic Assay Development: Employed in the development of diagnostic kits for lysosomal storage disorders, such as α-mannosidosis.
• Pharmaceutical Screening: Facilitates high-throughput screening for potential glycosidase inhibitors as therapeutic candidates.
• Quality Control in Bioprocessing: Monitors enzyme activity and purity in the production of recombinant proteins and other biologics.
• Glycobiology Studies: Aids in the investigation of glycan structure, function, and processing on glycoproteins.

Basic Information

Product Name	4-Nitrophenyl 6-o-(A-D-Mannopyranosyl)-A-D-Mannopyranoside
CAS No.	72647-96-2
Molecular Formula	C18H25NO13
Molecular Weight	463.39 g/mol
Synonyms	p-Nitrophenyl 6-O-α-D-mannopyranosyl-α-D-mannopyranoside; 4-Nitrophenyl α-D-mannobioside; PNPM; 6-O-α-D-Mannopyranosyl-α-D-mannopyranoside 4-nitrophenyl ester; α-D-Mannobioside, 4-nitrophenyl; 4-Nitrophenyl α-mannobioside
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl 6-o-(A-D-Mannopyranosyl)-A-D-Mannopyranoside is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.