Description

Chaetoglobosink is a potent secondary metabolite belonging to the cytochalasan alkaloid class, primarily isolated from fungi of the *Chaetomium* genus. This compound is of significant interest in biochemical research and pharmaceutical development due to its notable biological activities, including its role as a cytoskeleton disruptor. It serves as a critical reference standard and research material for scientists in pharmacology, cell biology, and natural product chemistry, enabling the study of cellular processes and the discovery of new therapeutic agents.

Application

• Pharmacological Research: Used as a reference standard in studies investigating cytoskeletal dynamics, cell division, and apoptosis.
• Biochemical Assay Development: Serves as a key reagent and positive control in assays targeting actin polymerization and microfilament function.
• Natural Product Isolation & Identification: Acts as a critical analytical standard for the identification and quantification of cytochalasans in fungal extracts and complex matrices.
• Drug Discovery & Mechanism of Action Studies: Employed in high-throughput screening and target validation for programs focused on oncology and anti-infective agents.
• Academic & Institutional Research: Essential for universities and research institutes conducting fundamental research in cell biology and mycotoxin analysis.

Basic Information

Product Name	Chaetoglobosink
CAS No.	72509-61-6
Molecular Formula	C₃₂H₃₆N₂O₅
Molecular Weight	528.64 g/mol
Synonyms	Chaetoglobosin K; NSC 332598; Cytochalasin from Chaetomium globosum; [13aR-(13aα,14β,16aα)]-14,16a-Dihydro-14-hydroxy-13a,16a-dimethyl-8,19-bis(methylene)-11,20-dioxa-4-azacyclooctadeca-1(17),2,4,15-tetraene-3,7,18-trione
EINECS	Contact for details

Quality Control

Our Chaetoglobosink is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment, ensuring full traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.