Description

5α,9α-Dihydroxymatrine is a structurally modified derivative of the natural alkaloid matrine, characterized by the introduction of two hydroxyl groups at specific positions on its tetracyclic quinolizidine scaffold. This modification significantly enhances its biological activity and alters its physicochemical profile, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for its potential in creating novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel anti-inflammatory, antiviral, and anti-tumor drug candidates.
• Biomedical Research: Used as a reference standard and active probe in pharmacological studies to investigate structure-activity relationships (SAR) of matrine derivatives.
• Agrochemical Development: Serves as a precursor for developing new, potentially bioactive plant growth regulators or natural product-based pesticides.
• Natural Product Chemistry: A crucial compound for the semi-synthesis and structural modification of other Sophora alkaloids.
• Cosmeceutical Ingredients: Investigated for potential use in advanced skincare formulations targeting specific biological pathways.

Basic Information

Product Name	5α,9α-Dihydroxymatrine
CAS No.	72362-00-6
Molecular Formula	C15H24N2O3
Molecular Weight	280.36 g/mol
Synonyms	5α,9α-Dihydroxymatrine; Matrine-5α,9α-diol; (5α,9α)-Dihydroxymatrine; 5α,9α-Dihydroxy-matrine; Sophoridine derivative; 5,9-Dihydroxymatrine; 5α,9α-Dihydroxy-7,11-dehydromatridin-15-one
EINECS	Contact for details

Quality Control

Our 5α,9α-Dihydroxymatrine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect the hygroscopic and light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.