Description

5-Pregnan-3A,21-Diol-20-One-17A,D3 CAS NO 72205-58-4 is a high-purity steroid derivative, specifically a pregnane diol ketone, valued for its role as a critical intermediate in advanced pharmaceutical synthesis. This compound is essential for researchers and manufacturers developing novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease. Key industries that rely on this precise chemical building block include pharmaceutical R&D, contract manufacturing organizations (CMOs), and fine chemical producers.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of specialized steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in biochemical research to study steroid metabolism, receptor interactions, and pathway modulation.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical laboratories.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create more complex molecular architectures with specific biological activity.
• Metabolic Pathway Studies: Utilized in preclinical studies to investigate enzymatic processes related to pregnane derivatives.

Basic Information

Product Name	5-Pregnan-3A,21-Diol-20-One-17A,D3
CAS No.	72205-58-4
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	17α,21-Dihydroxy-5β-pregnan-20-one; 5β-Pregnane-3α,17α,21-triol-20-one; 3α,17α,21-Trihydroxy-5β-pregnan-20-one; Tetrahydrodeoxycorticosterone; 5β-Tetrahydrodeoxycorticosterone; THDOC; 3α,21-Dihydroxy-5β-pregnan-20-one-17α-ol
EINECS	Contact for details

Quality Control

Our 5-Pregnan-3A,21-Diol-20-One-17A,D3 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. While produced to meet exacting internal standards, specifications can be aligned with client requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.