Description

n-Acetylglucosaminylphosphorylundecaprenol is a specialized, high-purity biochemical intermediate essential for research and development in bacterial cell wall biosynthesis. This compound matters as a critical lipid-linked precursor in the synthesis of peptidoglycan, a key structural component of bacterial membranes. It is primarily needed by pharmaceutical researchers, microbiologists, and industrial biochemists working on novel antibiotic development, enzyme mechanism studies, and the investigation of bacterial growth pathways.

Application

• Biochemical Research: As a key substrate for studying the enzymatic activity of MurG and other transferases involved in the peptidoglycan biosynthesis pathway.
• Antibiotic Discovery: Used in high-throughput screening assays to identify and characterize new classes of antibacterial agents that target cell wall formation.
• Enzymology Studies: Serves as a critical reagent for kinetic and mechanistic studies of membrane-associated glycosyltransferases.
• Metabolic Pathway Analysis: Employed in tracing and analyzing the complex steps of bacterial cell wall assembly in vitro.
• Pharmaceutical Development: Acts as a reference standard and process intermediate in the development of therapeutic agents targeting multidrug-resistant bacteria.
• Academic Research: Utilized in university and institutional labs for fundamental research into microbiology and structural biology.

Basic Information

Product Name	n-Acetylglucosaminylphosphorylundecaprenol
CAS No.	72165-46-9
Molecular Formula	C59H101NO13P
Molecular Weight	1063.4 g/mol (approx.)
Synonyms	Lipid I; Undecaprenyl-diphospho-N-acetylglucosamine; UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase substrate; N-Acetylglucosaminyl-diphospho-undecaprenol; GlcNAc-PP-Undecaprenol; 2-Acetamido-2-deoxy-D-glucopyranosyl dihydrogen diphosphate undecaprenol; Bacterial cell wall precursor Lipid I; (2R,3R,4R,5S,6R)-5-Acetamido-2-[[(2R,3S,4R,5R)-5-[[[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4-diol
EINECS	Contact for details

Quality Control

Our n-Acetylglucosaminylphosphorylundecaprenol is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled, dry environment to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in chloroform/methanol/water mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.