Description

Globotriaosylceramide Porcine is a high-purity glycosphingolipid, specifically a trihexosylceramide, isolated from porcine tissue. This compound serves as a critical reference standard and research reagent in the study of lysosomal storage disorders and glycolipid biology. It is essential for researchers and manufacturers in the pharmaceutical and life science sectors who require a reliable, well-characterized standard for analytical method development, diagnostic assay calibration, and biochemical research. The product is supplied with comprehensive analytical documentation to ensure traceability and reproducibility in sensitive applications.

Application

• Biochemical Research: Used as a substrate or standard in enzymatic assays to study glycosphingolipid metabolism and related enzyme activities (e.g., α-galactosidase A).
• Diagnostic Development: Serves as a critical calibrant and control material in the development of diagnostic kits for Fabry disease and other sphingolipidoses.
• Pharmaceutical R&D: Acts as a reference compound in drug discovery programs targeting lysosomal storage diseases, for potency testing and mechanism-of-action studies.
• Quality Control: Employed as a system suitability standard in analytical laboratories to validate HPLC, LC-MS, or TLC methods for glycolipid analysis.
• Cell Biology Studies: Utilized in research to investigate the role of globotriaosylceramide in cell signaling, membrane structure, and pathogen recognition.

Basic Information

Product Name	Globotriaosylceramide Porcine
CAS No.	71965-57-6
Molecular Formula	C47H89NO13
Molecular Weight	876.21 g/mol
Synonyms	Gb3 Ceramide (Porcine); Globotriaosylceramide (Porcine); α-D-Galactosyl-(1→4)-β-D-galactosyl-(1→4)-β-D-glucosylceramide (Porcine); Ceramide Trihexoside (CTH, Porcine); Fabry Disease Lipid; GL-3; PK antigen; CD77; C24:0-Gb3 (Porcine, typical fatty acid chain); Porcine Kidney Gb3
EINECS	Contact for details

Quality Control

Our Globotriaosylceramide Porcine is produced and handled under strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, mass spectrometry (MS), and NMR to confirm identity, purity, and structural integrity. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing batch-specific results. Our quality commitment ensures the material is suitable for demanding research and diagnostic applications where consistency and reliability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 5.0%
Specific Optical Rotation	Contact for details
Heavy Metals	< 20 ppm
Biological Activity	Suitable for enzyme assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.