Description

(S)-n-[4-[[(2-Amino-1,4,5,6,7,8-Hexahydro-4-Oxo-6-Pteridinyl)Methyl]Amino]Benzoyl]-L-Glutamic Acid is a high-purity, chemically defined reference standard and pharmaceutical intermediate. This compound is critical for research and development in the life sciences sector, particularly for its role in biochemical pathways. It is primarily sought by manufacturers and research institutions engaged in the synthesis of specialized therapeutics and analytical method development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted therapeutic agents and folate analogs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway analysis.
• Analytical Standard: Serves as a high-purity calibrant for quality control testing in pharmaceutical manufacturing (HPLC, LC-MS).
• Life Science Reagent: Employed in cell culture media studies and as a tool compound for investigating specific biological mechanisms.
• Preclinical Development: Utilized in the formulation and testing of novel drug candidates during early-stage R&D.

Basic Information

Product Name	(S)-n-[4-[[(2-Amino-1,4,5,6,7,8-Hexahydro-4-Oxo-6-Pteridinyl)Methyl]Amino]Benzoyl]-L-Glutamic Acid
CAS No.	71963-69-4
Molecular Formula	C₂₀H₂₅N₉O₆
Molecular Weight	487.47 g/mol
Synonyms	L-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-; (S)-N-(4-(((2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl)methyl)amino)benzoyl)glutamic acid; 6-[(4-{[(1S)-1,5-Dicarboxy-3-pentanyl]carbamoyl}phenyl)amino]methyl]-2-amino-5,6,7,8-tetrahydro-4(3H)-pteridinone; 6-[(4-{[(1S)-1,5-Dicarboxy-3-pentyl]carbamoyl}phenyl)amino]methyl]-2-amino-5,6,7,8-tetrahydro-4(3H)-pteridinone; Folate analog intermediate; Tetrahydrofolate derivative.
EINECS	Contact for details

Quality Control

Our (S)-n-[4-[[(2-Amino-1,4,5,6,7,8-Hexahydro-4-Oxo-6-Pteridinyl)Methyl]Amino]Benzoyl]-L-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.