Description

1-Valeryl-5-Fluorouracil is a fluorinated pyrimidine derivative and a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in the development of novel chemotherapeutic agents and targeted drug delivery systems. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in oncology drug discovery and the production of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation fluorouracil prodrugs and anti-cancer compounds.
• Oncology Research: Used in biochemical and pharmacological research to study structure-activity relationships and metabolic pathways of fluoropyrimidines.
• API Manufacturing: Serves as a precursor in the controlled production of specialized active pharmaceutical ingredients for targeted cancer therapies.
• Chemical Synthesis: Employed in organic synthesis for introducing the valeryl-fluorouracil moiety into more complex molecular architectures.
• Drug Delivery Systems: Investigated for use in prodrug formulations designed to improve bioavailability and reduce systemic toxicity.

Basic Information

Product Name	1-Valeryl-5-Fluorouracil
CAS No.	71861-75-1
Molecular Formula	C10H13FN2O3
Molecular Weight	228.22 g/mol
Synonyms	5-Fluoro-1-valeryluracil; 1-Pentanoyl-5-fluorouracil; 5-Fluorouracil-1-valerate; 5-FU-1-valerate; Valerylfluorouracil; N1-Valeryl-5-fluorouracil; 1-(Pentanoyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 1-Valeryl-5-Fluorouracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.