Description

Hydroxymethylbilane is a key linear tetrapyrrole intermediate in the biosynthesis of vital porphyrin compounds such as heme and chlorophyll. Its precise chemical structure makes it an essential building block for research and development in biochemistry and pharmaceuticals. This high-purity compound is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and advanced chemical synthesis sectors.

Application

• Biochemical Research: Critical intermediate for studying the heme and chlorophyll biosynthetic pathways.
• Pharmaceutical Development: Used as a reference standard and precursor in the development of porphyrin-based drugs and diagnostic agents.
• Enzyme Studies: Serves as a substrate for enzymes like uroporphyrinogen III synthase in mechanistic and kinetic studies.
• Metabolic Disorder Research: Employed in research models for porphyrias and other disorders related to tetrapyrrole metabolism.
• Chemical Synthesis: Acts as a sophisticated starting material for the synthesis of complex porphyrin derivatives and analogs.
• Academic & Industrial R&D: Fundamental tool in university laboratories and corporate R&D centers focused on bioinorganic chemistry and photodynamic therapy research.

Basic Information

Product Name	Hydroxymethylbilane
CAS No.	71861-60-4
Molecular Formula	C40H46N4O17
Molecular Weight	854.81 g/mol
Synonyms	Hydroxymethylbilane; Preuroporphyrinogen; HMB; 1-Hydroxymethylbilane; Uroporphyrinogen III precursor; Linear hydroxymethylbilane; Tetrapyrrole biosynthesis intermediate
EINECS	Contact for details

Quality Control

Our Hydroxymethylbilane is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Light-sensitive solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.