Description

1-Palmitoyl-2-(2-Azido-4-Nitro)Benzoyl-Glycero-3-Phosphocholine is a specialized, functionalized phospholipid derivative designed for advanced biochemical and biophysical research. This compound is of significant value for its role as a photoactivatable or crosslinking probe in membrane studies, enabling precise investigations into lipid-protein interactions and membrane dynamics. It is primarily needed by researchers and developers in the fields of lipidomics, structural biology, and pharmaceutical development, where controlled molecular manipulation is critical.

Application

• Membrane Biophysics Research: As a photoactivatable lipid probe for studying lipid bilayer properties, phase behavior, and domain formation.
• Protein-Lipid Interaction Studies: Used to covalently crosslink and identify proteins that interact with specific membrane environments or lipid microdomains.
• Lipidomics & Analytical Standards: Serves as a high-purity reference standard for mass spectrometry-based lipid identification and quantification.
• Drug Delivery System Development: A functional component in the design of targeted liposomal or nanoparticle delivery systems for controlled release applications.
• Bioconjugation & Labeling: The azido group allows for site-specific conjugation via click chemistry (e.g., with alkynes) for attaching fluorescent tags or other functional moieties.
• Model Membrane Assembly: Incorporation into artificial membranes (liposomes, supported lipid bilayers) to create systems with specific, inducible properties.

Basic Information

Product Name	1-Palmitoyl-2-(2-Azido-4-Nitro)Benzoyl-Glycero-3-Phosphocholine
CAS No.	71761-11-0
Molecular Formula	C₃₃H₅₄N₅O₁₀P
Molecular Weight	727.79 g/mol
Synonyms	Azido Nitro Benzoyl Phosphatidylcholine; 1-Palmitoyl-2-[2-(azido)-4-nitrobenzoyl]-sn-glycero-3-phosphocholine; Photoactivatable PC Lipid; ANB-PC; 2-(2-Azido-4-nitrobenzoyl)-1-palmitoyl-sn-glycero-3-phosphocholine; Functionalized Phospholipid; Crosslinking Phosphatidylcholine; Nitrophenylazido Phospholipid
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-(2-Azido-4-Nitro)Benzoyl-Glycero-3-Phosphocholine is produced under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous analytical standards, and specifications can be tailored to meet specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its strictly light-sensitive and strong oxidizer properties, this material must be stored in opaque containers under an inert atmosphere (e.g., argon or nitrogen) at -20°C or below for long-term stability. Avoid exposure to moisture, heat, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, DMSO, ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.