Description

Chromozym Pl is a highly specific chromogenic substrate designed for the assay of plasmin and related serine proteases. This compound matters for its critical role in enabling precise, quantitative measurement of enzymatic activity in research and diagnostic settings. It is needed by professionals in pharmaceutical R&D, clinical diagnostics, and biochemical research for applications in fibrinolysis studies, thrombosis research, and quality control of biopharmaceuticals.

Application

• Plasmin Activity Assays: Primary substrate for the specific and sensitive colorimetric or spectrophotometric determination of plasmin activity in biological samples.
• Fibrinolysis Research: Used in laboratory studies to investigate the fibrinolytic system, clot dissolution mechanisms, and related pathologies.
• Diagnostic Kit Component: Incorporated into commercial and in-house diagnostic kits for measuring plasminogen/plasmin levels in clinical settings.
• Serine Protease Profiling: Serves as a tool for characterizing the specificity and inhibition of plasmin and other trypsin-like enzymes.
• Pharmaceutical Development: Employed in the quality control and potency testing of thrombolytic drugs and related biotherapeutics.
• Biochemical Research: Fundamental reagent for enzymatic studies, kinetic analysis, and inhibitor screening in academic and industrial laboratories.

Basic Information

Product Name	Chromozym Pl
CAS No.	71663-39-3
Molecular Formula	C30H37N7O8
Molecular Weight	623.66 g/mol
Synonyms	D-Valyl-L-leucyl-L-lysyl-4-nitroanilide diacetate; Tosyl-Gly-Pro-Lys-4-nitroanilide acetate (common misnomer); S-2251 (alternative designation); H-D-Val-Leu-Lys-pNA • 2AcOH; Plasmin Substrate; Chromogenic Substrate for Plasmin; Boc-Val-Leu-Lys-pNA (related precursor)
EINECS	Contact for details

Quality Control

Our Chromozym Pl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term stability, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO
Functional Activity	Conforms to performance standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.