Description

(9H-Fluoren-9-yl)methyl 4-methylbenzene-1-sulfonate is a specialized organic sulfonate ester widely used as a key protecting group reagent in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates for the development of pharmaceuticals and complex organic molecules. It is primarily utilized by the pharmaceutical, agrochemical, and fine chemical industries for the protection of hydroxyl groups during multi-step synthetic sequences, ensuring reaction fidelity and yield.

Application

• Pharmaceutical Intermediate Synthesis: Serves as a crucial reagent for the introduction of the Fmoc (9-fluorenylmethoxycarbonyl) protecting group in peptide and oligonucleotide synthesis.
• Agrochemical Development: Used in the multi-step synthesis of complex active ingredients where selective protection of functional groups is required.
• Fine Chemical Manufacturing: Acts as a building block and protecting group agent in the production of specialty chemicals, dyes, and advanced materials.
• Academic & Industrial R&D: A staple reagent in research laboratories for method development and the synthesis of novel organic compounds.
• Process Chemistry: Employed in scalable synthetic routes for the production of active pharmaceutical ingredients (APIs) under controlled GMP-like conditions.

Basic Information

Product Name	(9H-Fluoren-9-yl)methyl 4-methylbenzene-1-sulfonate
CAS No.	71532-40-6
Molecular Formula	C22H20O3S
Molecular Weight	364.46 g/mol
Synonyms	Fmoc-OTs; 9-Fluorenylmethyl p-Toluenesulfonate; N-(9-Fluorenylmethoxycarbonyloxy)succinimide p-Toluenesulfonate Salt; 4-Methylbenzenesulfonic Acid (9H-Fluoren-9-yl)methyl Ester; p-Toluenesulfonic Acid Fluoren-9-ylmethyl Ester; 9-Fluorenylmethyl Tosylate; Fmoc-OSu p-TsOH
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-yl)methyl 4-methylbenzene-1-sulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and cGMP-guided production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.