Description

1-Myristoyl-2-(12-n-(4-Azido-2-Nitrophenyl)Aminododecanoyl)Phosphatidylcholine is a specialized, photoactivatable phospholipid derivative designed for advanced biochemical and biophysical research. This compound matters for its unique ability to form covalent cross-links upon exposure to light, making it an essential tool for studying membrane dynamics, protein-lipid interactions, and for the site-specific labeling of biomolecules. It is primarily needed by research scientists and product developers in the fields of membrane biophysics, proteomics, and pharmaceutical R&D, particularly for creating stabilized liposomal structures or investigating lipid raft domains.

Application

• Membrane Protein Research: As a photo-crosslinker to trap and study transient protein-lipid interactions within artificial or cellular membranes.
• Liposome Stabilization: For the covalent stabilization of liposomal bilayers in drug delivery system development, enhancing particle integrity.
• Bioconjugation & Labeling: Site-specific covalent attachment of probes or tags to lipid assemblies for imaging and detection applications.
• Model Membrane Studies: Incorporation into lipid bilayers (e.g., supported lipid bilayers, vesicles) to investigate lipid dynamics and domain formation.
• Material Science: Surface functionalization and the creation of cross-linked thin films with specific biological recognition properties.
• Diagnostic Assay Development: Used in the fabrication of biosensors and assay platforms requiring stable, functionalized lipid interfaces.

Basic Information

Product Name	1-Myristoyl-2-(12-n-(4-Azido-2-Nitrophenyl)Aminododecanoyl)Phosphatidylcholine
CAS No.	71303-93-0
Molecular Formula	C45H80N6O10P
Molecular Weight	895.13 g/mol
Synonyms	1-Myristoyl-2-{12-[(4-Azido-2-nitrophenyl)amino]dodecanoyl}-sn-glycero-3-phosphocholine; NAP-DPPE Analog (Phosphatidylcholine version); 4-Azido-2-nitrophenylaminododecanoyl Phosphatidylcholine; Photoactivatable PC Lipid; ANP-DPPC; 1-Myristoyl-2-(12-((4-Azido-2-nitrophenyl)amino)dodecanoyl)-PC; Light-sensitive Phosphatidylcholine Derivative; Arylazido Phosphatidylcholine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 1-Myristoyl-2-(12-n-(4-Azido-2-Nitrophenyl)Aminododecanoyl)Phosphatidylcholine is characterized by advanced analytical techniques including NMR and Mass Spectrometry to confirm structure and purity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to a quality management system suitable for supplying research and development sectors.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and moisture. For long-term stability, desiccate the container. Allow the sealed vial to warm to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, DMSO; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.